Painful insulin jab may be replaced by capsule


So many drugs, especially those made of proteins, cannot be taken orally because they are broken down in the gastrointestinal tract before they can take effect.

Scientists have designed an oral capsule which can deliver insulin and other drugs – that usually have to be injected – to the lining of the small intestine and release them for uptake into the bloodstream.

The researchers at MIT, working with scientists from Danish pharmaceutical company Novo Nordisk, have designed a new drug capsule that can carry insulin or other protein drugs and protect them from the harsh environment of the gastrointestinal tract. It breaks down to reveal dissolvable microneedles carrying that attach to the intestinal wall and release drug.

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